Pre-Processing for Determining Acral Lentiginous Melanoma(ALM)

Management of Acral Lentiginous Melanoma

Cutaneous malignant melanoma is the most common cause of mortality from skin cancers in Caucasian populations. The incidence rates of malignant melanoma show considerable varia‐ tion worldwide. Annual incidence rates per 100,000 people vary between about 40 in Australia and New Zealand to about 20 in the United States [1,2]. In contrast, a significantly lower inci‐ dence rate has been reported ...

Progression from Acral Lentiginous Melanoma in situ to Invasive Acral Lentiginous Melanoma.

Acral lentiginous melanoma (ALM) is the most common type of cutaneous melanoma in Asians. The very early stage of ALM demonstrates only a proliferation of a few atypical melanocytes within the epidermis, and has been termed ALM in situ. A 74-year-old male patient presented with a pigmented lesion on the left great toe for 12 years, which had initially showed only a few scattered hyperplastic at...

Sequential Acral Lentiginous Melanomas of the Foot

A 64-year-old Japanese woman had a lightly brown-blackish pigmented macule (1.2 cm in diameter) on the left sole of her foot. She received surgical excision following a diagnosis of acral lentiginous melanoma (ALM), which was confirmed histopathologically. One month after the operation, a second melanoma lesion was noticed adjacent to the grafted site. Histopathologically, the two lesions had n...

Current Surgical Management of Acral Lentiginous Melanoma

Multiple Primary Acral Lentiginous Melanomas (MPALM)

We present a rare case of a patient with multiple primary acral lentiginous melanomas of the foot. We would like to highlight the importance of whole-skin examination in all patients, even by the general practitioners, aiming the maximal early detection of acral lentiginous melanomas, considering their rapid progression, early metastatic spread and extremely poor prognosis. It can be extrapolat...